Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464926 | 0.80 | LMNA (0.47) | PKMLMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL8464469 | 0.78 | ALDH1A1 (0.41) | KDM4ELMNAHPGDHSD17B10CA1 | |
| SCHEMBL10590409 | 0.77 | PARP1 (0.41) | PARP1MEP1BPKMKDM4ECES2 | |
| SCHEMBL8463349 | 0.77 | GAA (0.40) | KDM4ELMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL8464312 | 0.77 | CA12 (0.35) | CES2LMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL8460910 | 0.77 | MEN1 (0.38) | KDM4ECES2CES1HPGDHSD17B10 | |
| SCHEMBL3195282 | 0.75 | PKM (0.47) | PKMCES2CES1TET2CA3 | |
| Sulfamide SCHEMBL8460578 | 0.74 | ALDH1A1 (0.46) | PKMKDM4ELMNAHPGDHIF1A | |
| SCHEMBL3935279 | 0.74 | PKM (0.46) | PKMCES2CES1TET2CA3 | |
| SCHEMBL6359929 | 0.74 | HSD17B10 (0.49) | PARP1KDM4ELMNAHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |