Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460490 | 0.77 | PARP1 (0.33) | TSHRCES2CA1CA2MMP1 | |
| SCHEMBL3204890 | 0.77 | PDE2A (0.43) | MEN1KMT2AALDH1A1TSHRATM | |
| SCHEMBL3190051 | 0.77 | CES2 (0.52) | MEN1KMT2AALDH1A1TSHRATM | |
| SCHEMBL8464926 | 0.76 | LMNA (0.47) | ALDH1A1L3MBTL1CA1CA2HPGD | |
| SCHEMBL27855804 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1TSHRATM | |
| SCHEMBL27872324 | 0.75 | EPHX2 (0.43) | MEN1KMT2AALDH1A1TSHRATM | |
| Hydrochloric Acid SCHEMBL28320494 | 0.75 | PDE2A (0.42) | MEN1KMT2AALDH1A1TSHRATM | |
| SCHEMBL1363127 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TSHRATM | |
| SCHEMBL27256998 | 0.75 | MCL1 (0.46) | MEN1KMT2AMCL1 | |
| SCHEMBL8464469 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRCA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |