Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459098 | 0.74 | MAPT (0.55) | ALDH1A1MAPTDHODHKDM4ELMNA | |
| SCHEMBL4784189 | 0.72 | APAF1 (0.50) | ALDH1A1MAPTDHODHKDM4ELMNA | |
| SCHEMBL11490745 | 0.71 | MAPT (0.46) | ALDH1A1MAPTITGA4KDM4ELMNA | |
| SCHEMBL8446033 | 0.70 | APEX1 (0.38) | ALDH1A1MAPTDHODHKDM4ELMNA | |
| SCHEMBL29359488 | 0.70 | APEX1 (0.38) | ALDH1A1MAPTDHODHKDM4ELMNA | |
| SCHEMBL14178915 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MAPTITGA4KDM4ELMNA | |
| SCHEMBL29355977 | 0.68 | DHODH (0.51) | ALDH1A1MAPTDHODHKDM4ELMNA | |
| SCHEMBL4978926 | 0.65 | ALDH1A1 (0.40) | ALDH1A1MAPTITGA4KDM4ELMNA | |
| SCHEMBL4978923 | 0.65 | ALDH1A1 (0.40) | ALDH1A1MAPTITGA4KDM4ELMNA | |
| SCHEMBL819660 | 0.63 | MAPT (0.48) | ALDH1A1MAPTITGA4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |