Sugi Predict

Sugi Predict / Compounds / SCHEMBL29359488

SCHEMBL29359488

SCHEMBL29359488

C=CC(C)(C)C1=C(OC(C)=O)C(=O)c2ccccc2C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.38
▸ ALDH1A1 P00352 6/20 0.37
▸ MAPT P10636 6/20 0.37
▸ KDM4E B2RXH2 5/20 0.37
▸ HPGD P15428 3/20 0.37
▸ RAB9A P51151 3/20 0.37
▸ LMNA P02545 3/20 0.37
▸ BLM P54132 3/20 0.37
▸ CYP1A2 P05177 3/20 0.37
▸ CYP2C9 P11712 3/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ CYP2D6 P10635 2/20 0.37
▸ CYP2C19 P33261 2/20 0.37
▸ HIF1A Q16665 2/20 0.37
▸ CDC25A P30304 2/20 0.37
▸ CDC25B P30305 2/20 0.37
▸ MAP2K7 O14733 1/20 0.37
▸ GMNN O75496 1/20 0.37
▸ TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8446033 1.00 APEX1 (0.38) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL8459098 0.81 MAPT (0.55) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL8459717 0.78 LMNA (0.45) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL11365625 0.77 MAPT (0.54) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL4784189 0.76 APAF1 (0.50) ALDH1A1MAPTKDM4EHPGDRAB9A
SCHEMBL686744 0.72 CDC25B (0.59) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL29355977 0.72 DHODH (0.51) ALDH1A1MAPTKDM4ERAB9ALMNA
SCHEMBL11616539 0.72 MAPT (0.50) APEX1ALDH1A1MAPTKDM4EHPGD
SCHEMBL8463187 0.70 ALDH1A1 (0.33) ALDH1A1MAPTKDM4EHPGDRAB9A
SCHEMBL10959287 0.69 IDO1 (0.54) APEX1ALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036637-A Polymorphs 先正达农作物保护股份公司 2026-05-15 — — CN disclosed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 — — US disclosed
EP-4717089-A2 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-04-01 — — EP disclosed
EP-4380933-B1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-02-18 — — EP disclosed
US-20260020567-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-22 — — US disclosed
US-12528778-B2 Microbiocidal derivatives SYNGENTA CROP PROTECTION AG (CH) 2026-01-20 — — US disclosed
US-12497406-B2 Microbiocidal derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-12-16 — — US disclosed
US-20250368652-A1 MICROBIOCIDAL BICYCLIC HETEROCYCLIC CARBOXAMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-12-04 — — US disclosed
EP-4655284-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-12-03 — — EP disclosed
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
WO-2022058580-A1 MICROBIOCIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-24 — — WO disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 — — CN disclosed
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-08 — — US disclosed
US-11259524-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-01 — — US disclosed
CN-114072384-A Microbicidal picolinamide derivatives 先正达农作物保护股份公司 2022-02-18 — — CN disclosed
EP-3947371-A1 MICROBIOCIDAL THIAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2022-02-09 — — EP disclosed
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-02-08 — — US disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
CN-108368098-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368652-A1 MICROBIOCIDAL BICYCLIC HETEROCYCLIC CARBOXAMIDE DERIVATIVES CASP1, ARG2, MPO APEX1 762/4885ALDH1A1 582/4885MAPT 4691/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC APEX1 3361/4885ALDH1A1 845/4885MAPT 2250/4885
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 APEX1 595/4885ALDH1A1 1059/4885MAPT 3249/4885
US-12528778-B2 Microbiocidal derivatives CCR1, CCR6, CCRL2 APEX1 560/4885ALDH1A1 309/4885MAPT 4845/4885
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 APEX1 595/4885ALDH1A1 1059/4885MAPT 3249/4885
US-20260020567-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES CYP51A1, CYP4B1, CYP8B1 APEX1 3624/4885ALDH1A1 2663/4885MAPT 914/4885
US-12497406-B2 Microbiocidal derivatives MPO, PRF1, MSR1 APEX1 400/4885ALDH1A1 554/4885MAPT 4658/4885
US-11259524-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 APEX1 361/4885ALDH1A1 476/4885MAPT 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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