Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359488 | 1.00 | APEX1 (0.38) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8459098 | 0.81 | MAPT (0.55) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8459717 | 0.78 | LMNA (0.45) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11365625 | 0.77 | MAPT (0.54) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4784189 | 0.76 | APAF1 (0.50) | ALDH1A1MAPTKDM4EHPGDRAB9A | |
| SCHEMBL686744 | 0.72 | CDC25B (0.59) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL29355977 | 0.72 | DHODH (0.51) | ALDH1A1MAPTKDM4ERAB9ALMNA | |
| SCHEMBL11616539 | 0.72 | MAPT (0.50) | APEX1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8463187 | 0.70 | ALDH1A1 (0.33) | ALDH1A1MAPTKDM4EHPGDRAB9A | |
| SCHEMBL10959287 | 0.69 | IDO1 (0.54) | APEX1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318788-A1 | Microcapsule | FOOD AND ENVIRONMENT RESEARCH AGENCY (FERA) REPRESENTING THE SECRETARY OF STATE FOR FOOD, ENVIRONMENT AND RURAL AFFAIRS, THE (GB) | 2008-12-25 | — | — | US | disclosed |
| US-20080318788-A1 | Microcapsule | FOOD AND ENVIRONMENT RESEARCH AGENCY (FERA) REPRESENTING THE SECRETARY OF STATE FOR FOOD, ENVIRONMENT AND RURAL AFFAIRS, THE (GB) | 2008-12-25 | — | — | US | disclosed |
| US-20080076666-A1 | Formulation | FOOD AND ENVIRONMENT RESEARCH AGENCY (FERA) REPRESENTING THE SECRETARY OF STATE FOR FOOD, ENVIRONMENT AND RURAL AFFAIRS, THE (GB) | 2008-03-27 | — | — | US | disclosed |
| US-20080076666-A1 | Formulation | FOOD AND ENVIRONMENT RESEARCH AGENCY (FERA) REPRESENTING THE SECRETARY OF STATE FOR FOOD, ENVIRONMENT AND RURAL AFFAIRS, THE (GB) | 2008-03-27 | — | — | US | disclosed |
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0759898-B1 | NAPHTHOQUINONE DERIVATIVES | BTG INT LTD (GB) | 1999-07-14 | — | — | EP | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| US-5834515-A | PESTICIDE; TREATING WITH A PLANT EXTRACT FROM A CALCEOLARIA SPECIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318788-A1 | Microcapsule | CAPG, CHMP4B, CAT | APEX1 4362/4885ALDH1A1 4137/4885MAPT 438/4885 |
| US-20080076666-A1 | Formulation | UROD, GUSB, GLA | APEX1 4006/4885ALDH1A1 902/4885MAPT 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.