SCHEMBL29355977

SCHEMBL29355977

C=CC(C)(C)C1=C(O)c2ccccc2C(=O)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 6/20 0.51
▸ P2RX7 Q99572 3/20 0.44
▸ APAF1 O14727 2/20 0.44
▸ TDP2 O95551 2/20 0.44
▸ MEN1 O00255 5/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ MAPT P10636 5/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ CDC25B P30305 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ CDC25A P30304 1/20 0.43
▸ RPS6KA3 P51812 1/20 0.43
▸ GLO1 Q04760 1/20 0.43
▸ GPR35 Q9HC97 1/20 0.43
▸ USP2 O75604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4784189 0.88 APAF1 (0.50) DHODHP2RX7APAF1TDP2MEN1
SCHEMBL12715781 0.76 DHODH (0.41) DHODHP2RX7APAF1TDP2MEN1
SCHEMBL13382708 0.75 DHODH (0.43) DHODHP2RX7APAF1TDP2MEN1
SCHEMBL8459098 0.73 MAPT (0.55) DHODHTDP2MEN1KMT2AMAPT
SCHEMBL29359488 0.72 APEX1 (0.38) DHODHAPAF1TDP2MEN1KMT2A
SCHEMBL8446033 0.72 APEX1 (0.38) DHODHAPAF1TDP2MEN1KMT2A
SCHEMBL3332517 0.71 DNMT1 (0.44) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL3333270 0.70 PTPN1 (0.33) DHODHMAPTPOLBHIF1ACES2
SCHEMBL14439382 0.69 LCK (0.46) KMT2AMAPTALDH1A1SMN1; SMN2PKM
SCHEMBL8463187 0.68 ALDH1A1 (0.33) DHODHMAPTALDH1A1CDC25BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036637-A Polymorphs 先正达农作物保护股份公司 2026-05-15 — — CN disclosed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 — — US disclosed
EP-4717089-A2 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-04-01 — — EP disclosed
EP-4380933-B1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-02-18 — — EP disclosed
US-20260020567-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-22 — — US disclosed
US-12528778-B2 Microbiocidal derivatives SYNGENTA CROP PROTECTION AG (CH) 2026-01-20 — — US disclosed
US-12497406-B2 Microbiocidal derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-12-16 — — US disclosed
US-20250368652-A1 MICROBIOCIDAL BICYCLIC HETEROCYCLIC CARBOXAMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-12-04 — — US disclosed
EP-4655284-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-12-03 — — EP disclosed
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
WO-2022058580-A1 MICROBIOCIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-24 — — WO disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 — — CN disclosed
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-08 — — US disclosed
US-11259524-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-01 — — US disclosed
CN-114072384-A Microbicidal picolinamide derivatives 先正达农作物保护股份公司 2022-02-18 — — CN disclosed
EP-3947371-A1 MICROBIOCIDAL THIAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2022-02-09 — — EP disclosed
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-02-08 — — US disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
CN-108368098-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 — — CN disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368652-A1 MICROBIOCIDAL BICYCLIC HETEROCYCLIC CARBOXAMIDE DERIVATIVES CASP1, ARG2, MPO DHODH 267/4885P2RX7 135/4885APAF1 279/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC DHODH 2466/4885P2RX7 788/4885APAF1 3217/4885
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 DHODH 534/4885P2RX7 292/4885APAF1 1601/4885
US-12528778-B2 Microbiocidal derivatives CCR1, CCR6, CCRL2 DHODH 787/4885P2RX7 1260/4885APAF1 1469/4885
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 DHODH 534/4885P2RX7 292/4885APAF1 1601/4885
US-20260020567-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES CYP51A1, CYP4B1, CYP8B1 DHODH 1281/4885P2RX7 874/4885APAF1 2185/4885
US-12497406-B2 Microbiocidal derivatives MPO, PRF1, MSR1 DHODH 313/4885P2RX7 843/4885APAF1 194/4885
US-11259524-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 DHODH 309/4885P2RX7 1025/4885APAF1 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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