Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | CDC25A | P30304 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 3/20 | 0.55 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446033 | 0.81 | APEX1 (0.38) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL29359488 | 0.81 | APEX1 (0.38) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL9629357 | 0.80 | MAPT (0.65) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL4784189 | 0.78 | APAF1 (0.50) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL8463187 | 0.74 | ALDH1A1 (0.33) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL29355977 | 0.73 | DHODH (0.51) | MAPTALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL29545010 | 0.73 | MAPT (1.00) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL571557 | 0.73 | MAPT (1.00) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL15289027 | 0.72 | MAPT (0.63) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL21232268 | 0.70 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |