Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.30 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8460425 | 0.98 | FUT7 (0.38) | FUT7GPR84KAT8GAAGRIN2D | |
| Zinc Ion SCHEMBL8462308 | 0.98 | FUT7 (0.38) | FUT7GPR84KAT8GAAGRIN2D | |
| Zinc Ion SCHEMBL9502067 | 0.93 | GRIN2D (0.34) | FUT7GPR84GAAGRIN2DGRIN2A | |
| SCHEMBL8464681 | 0.89 | FUT7 (0.42) | FUT7GPR84GAAGRIN2DGRIN2A | |
| SCHEMBL9502942 | 0.88 | KAT8 (0.41) | FUT7KAT8GAAGRIN2DGRIN2A | |
| Potassium Ion SCHEMBL8465183 | 0.87 | GAA (0.41) | FUT7GPR84GAAGRIN2DGRIN2A | |
| Zinc Ion SCHEMBL8464685 | 0.87 | GAA (0.41) | FUT7GPR84GAAGRIN2DGRIN2A | |
| SCHEMBL9501729 | 0.83 | GRIN2D (0.41) | GPR84KAT8GAAGRIN2DGRIN2A | |
| Zinc Ion SCHEMBL9504196 | 0.82 | GAA (0.42) | FUT7GAAGRIN2DGRIN2AGRIN2B | |
| SCHEMBL8465015 | 0.80 | FUT7 (0.45) | FUT7GPR84KAT8GRIN2DGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548906-B1 | Method for preparing nuclear-substituted salicylic acid metal salts and color developer for pressure-sensitive recording sheets | SANKO KAIHATSU KAGAKU KENK (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5393332-A | Salt of salicylic acid | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0548906-A2 | Method for preparing nuclear-substituted salicylic acids and metal salts thereof | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1993-06-30 | — | — | EP | disclosed |