Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 15/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 14/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8469666 | 0.89 | KEAP1 (0.48) | KEAP1NFE2L2LMNAL3MBTL1 | |
| SCHEMBL8076290 | 0.89 | KEAP1 (0.40) | KEAP1NFE2L2PIK3CGLMNACA12 | |
| SCHEMBL8469225 | 0.88 | ALDH1A1 (0.48) | KEAP1NFE2L2LMNAKDM4E | |
| SCHEMBL8469817 | 0.86 | KEAP1 (0.40) | KEAP1NFE2L2PIK3CGLMNAL3MBTL1 | |
| SCHEMBL8471272 | 0.82 | ALDH1A1 (0.46) | KEAP1NFE2L2LMNA | |
| SCHEMBL8469659 | 0.81 | LMNA (0.51) | KEAP1NFE2L2LMNAL3MBTL1KDM4E | |
| Bromide SCHEMBL8080918 | 0.78 | KEAP1 (0.45) | KEAP1NFE2L2CA12CA1CA2 | |
| SCHEMBL8076269 | 0.78 | ALDH1A1 (0.42) | KEAP1NFE2L2LMNAKDM4E | |
| SCHEMBL8470011 | 0.76 | ALDH1A1 (0.44) | KEAP1NFE2L2LMNAL3MBTL1KDM4E | |
| Bromide SCHEMBL8471510 | 0.76 | HSP90AA1 (0.50) | KEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |