Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013499 | 0.81 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7684228 | 0.71 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL7013018 | 0.67 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL8468997 | 0.60 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL7016669 | 0.60 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL1335872 | 0.59 | KMT2A (0.44) | — | |
| SCHEMBL11270418 | 0.59 | LMNA (0.53) | — | |
| SCHEMBL29492646 | 0.59 | LMNA (0.53) | — | |
| SCHEMBL14225796 | 0.59 | AURKA (0.41) | — | |
| Ammonia Solution, Strong SCHEMBL6433627 | 0.58 | THRB (0.41) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920429-A1 | SUBSTITUTED PYRIDO- OR PYRIMIDO-CONTAINING 6,6- OR 6,7-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998005661-A1 | SUBSTITUTED PYRIDO- OR PYRIMIDO-CONTAINING 6,6- OR 6,7-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1998-02-12 | — | — | WO | disclosed |