Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462729 | 0.92 | TSHR (0.50) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL25634365 | 0.83 | TSHR (0.42) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL26032461 | 0.74 | TSHR (0.47) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL3371689 | 0.72 | TSHR (0.44) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL105343 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL3367414 | 0.72 | TSHR (0.47) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL28705429 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| SCHEMBL3368017 | 0.72 | TSHR (0.44) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| Pivalate SCHEMBL332912 | 0.70 | TSHR (0.61) | TSHRALDH1A1CYP2C19CYP2D6HIF1A | |
| Pivalate SCHEMBL5116637 | 0.70 | TSHR (0.61) | TSHRALDH1A1CYP2C19CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8779166-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8536291-B2 | Hydrogel compositions and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-09-17 | — | — | US | disclosed |
| US-20130217853-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-22 | — | — | US | disclosed |
| US-8455612-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-8450504-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450505-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |
| US-20120322949-A1 | Hydrogel Compositions and Methods of Preparation Thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-12-20 | — | — | US | disclosed |
| US-8263715-B2 | Hydrogel compositions and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120178891-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | CENTRAL GLASS CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-8044194-B2 | Cyclic carbonyl monomers functionalized with carbohydrates, polymers derived therefrom, and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110054064-A1 | Hydrogel Compositions and Methods of Preparation Thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100317838-A1 | CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-5434276-A | Process for making N-acyl taurides | FINETEX, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| WO-1995018095-A1 | PROCESS FOR MAKING N-ACYL TAURIDES | FINETEX, INC. (US) | 1995-07-06 | — | — | WO | disclosed |
| US-4352759-A | CRYSTALLIZATION IN ALCOHOL, AMIDATION | CHASE MANHATTAN BANK, THE NATIONAL ASSOCIATION | 1982-10-05 | — | — | US | disclosed |
| US-4233229-A | REACTING ACID CHLORIDE, TAURINE SALT, ALKALI METAL HYDROXIDE; PRECIPITATING ALKALI METAL CHLORIDE | GAF CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| EP-0002675-A1 | Preparation of salt-free N-acyl taurines | GAF CORPORATION (US) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317838-A1 | CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF | FUT6, FUT5, WASF2 | TSHR 4657/4885ALDH1A1 557/4885CYP2C19 3302/4885 |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | TSHR 1728/4885ALDH1A1 618/4885CYP2C19 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.