Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037681 | 0.76 | TSHR (0.47) | CYP2D6CYP2C19LMNA | |
| SCHEMBL7935090 | 0.75 | LMNA (0.39) | SRCCYP2D6LMNAMAPK1L3MBTL1 | |
| SCHEMBL1270652 | 0.74 | TAAR1 (0.42) | CYP2D6LMNAL3MBTL1 | |
| SCHEMBL6914191 | 0.72 | ALDH1A1 (0.46) | SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL3454935 | 0.71 | TRPA1 (0.38) | SRCCYP2D6LMNAMAPK1TDP1 | |
| SCHEMBL2118480 | 0.70 | TAAR1 (0.39) | CYP2D6LMNAL3MBTL1 | |
| SCHEMBL9339406 | 0.70 | TAAR1 (0.50) | CYP2D6CYP2C19SLC6A3 | |
| SCHEMBL1645203 | 0.70 | TSHR (0.42) | CYP2D6LMNAL3MBTL1 | |
| SCHEMBL4660217 | 0.68 | ALDH1A1 (0.40) | SRCCYP2D6LMNATDP1L3MBTL1 | |
| 3,3-Diphenylpropanoic Acid SCHEMBL5283373 | 0.67 | GABBR2 (0.59) | SRCCYP2D6CYP2C19GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919552-A | Coated substrates and methods | XEROX CORPORATION (US) | 1999-07-06 | — | — | US | claimed |
| US-5919552-A | Coated substrates and methods | XEROX CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |