Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454935 | 0.74 | TRPA1 (0.38) | ALDH1A1LMNACYP2D6SRCMAPK1 | |
| SCHEMBL8470916 | 0.72 | SRC (0.43) | LMNACYP2D6SRCMAPK1 | |
| SCHEMBL11543107 | 0.72 | MTNR1A (0.58) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL4660217 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNACYP2D6SRCKDM4E | |
| SCHEMBL13950144 | 0.69 | RIPK1 (0.53) | ALDH1A1MTNR1AMTNR1BLMNAHPGD | |
| SCHEMBL270135 | 0.69 | RIPK1 (0.50) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7935090 | 0.69 | LMNA (0.39) | LMNACYP2D6SRCMAPK1KDM4E | |
| SCHEMBL1270652 | 0.68 | TAAR1 (0.42) | LMNACYP2D6KDM4E | |
| SCHEMBL23757780 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MTNR1AMTNR1BLMNAHPGD | |
| SCHEMBL7406300 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MTNR1AMTNR1BLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818423-B2 | LOW-MOLECULAR-WEIGHT C4-C6-KETONES DERIVATIZED WITH REMOVABLE GROUP ARE REACTED WITH CYANIDE GROUP DONOR IN PRESENCE OF HYDROXYNITRILE LYASE OR BY RACEMIC REACTION, ACIDIC HYDROLYSIS, OPTIONALLY RESOLUTION, AND CLEAVAGE OF THE GROUP | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) | 2004-11-16 | — | — | US | disclosed |
| US-20030092142-A1 | Process for the preparation of chiral alpha-hydroxycarboxylic acids | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2003-05-15 | — | — | US | disclosed |
| EP-1310477-A2 | Process for the preparation of chiral alpha-hydroxycarboxylic acids | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-05-14 | — | — | EP | disclosed |