SCHEMBL847484

SCHEMBL847484

O=[N+]([O-])c1cc2ccccc2o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 5/20 0.62
PAX8 Q06710 1/20 0.46
RAB9A P51151 2/20 0.46
MITF O75030 1/20 0.46
NOD2 Q9HC29 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
FLT3 P36888 1/20 0.46
CYP2A6 P11509 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
BRCA1 P38398 1/20 0.45
HIF1A Q16665 1/20 0.45
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
TYR P14679 1/20 0.44
DAO P14920 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL11807849 0.87 RAB9A (0.50) HNF4ARAB9AMITFNOD2TDP1
SCHEMBL16001173 0.85 HNF4A (0.58) HNF4APAX8RAB9AMITFNOD2
SCHEMBL28399285 0.77 MAOB (0.56) HNF4APAX8RAB9ATDP1SMN1; SMN2
SCHEMBL11095673 0.77 HNF4A (1.00) HNF4APAX8RAB9ATDP1SMN1; SMN2
SCHEMBL1046782 0.76 MAOA (0.54) RAB9ASMN1; SMN2CYP1A2MAPTKMT2A
SCHEMBL29163743 0.76 HNF4A (0.49) HNF4APAX8RAB9AMITFTDP1
SCHEMBL27607138 0.76 HNF4A (0.61) HNF4APAX8RAB9ASMN1; SMN2TP53
SCHEMBL5026929 0.76 HNF4A (0.57) HNF4AMITFTDP1SMN1; SMN2TP53
SCHEMBL28944458 0.76 HNF4A (0.49) HNF4APAX8TDP1POLBCA2
SCHEMBL28779909 0.76 MAOB (0.51) HNF4APAX8RAB9ASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930598-A Non-reactive near-infrared mitochondrial cristae tracking super-resolution fluorescent probe and application thereof 山东大学 2025-05-06 CN claimed
CN-222401110-U Mixed structure for preparing nitrobenzofuran 连云港海恒生化科技有限公司 2025-01-28 CN claimed
CN-222218884-U Nitrophenofuran Filtering structure for preparation 连云港海恒生化科技有限公司 2024-12-24 CN claimed
US-12162897-B2 1,4-sulfur-bridged polycyclic compounds containing dihydrobenzofuran structure, its preparation method and application thereof CHENGDU UNIVERSITY (CN) 2024-12-10 US claimed
CN-118561851-A Preparation method of polysubstituted indolo [2,3-b ] carbazole compound 湖南师范大学 2024-08-30 CN claimed
US-20240287099-A1 1,4-Sulfur-Bridged Polycyclic Compounds Containing Dihydrobenzofuran Structure, Its Preparation Method and Application Thereof CHENGDU UNIVERSITY (CN) 2024-08-29 US claimed
CN-116063312-A 2-phenyl-3 a,8 a-dihydrofuro [2,3-b ] benzofuran compound and preparation method thereof 浙大城市学院 2023-05-05 CN claimed
WO-2022167002-A1 1,4-SULFOBRIDGED POLYCYCLIC COMPOUND CONTAINING DIHYDROBENZOFURAN STRUCTURE, AND PREPARATION METHOD AND USE THEREFOR 成都大学 2022-08-11 WO claimed
CN-113444108-B 1, 4-sulfur bridge polycyclic compound containing dihydrobenzofuran structure, preparation method and application thereof 成都大学 2022-03-25 CN claimed
CN-113559054-A Active oxygen scavenging/responding allosteric self-assembly hydrogel and application thereof 南京工业大学 2021-10-29 CN claimed
CN-106967416-B The preparation method of titanium dioxide nano-particle fluorescence probe for DDT detection 合肥学院 2019-07-02 CN claimed
CN-103648530-B Protein-active agent conjugates and methods of making the same 乐高化学生物科学股份有限公司 2017-02-08 CN claimed
CN-105101961-A Method for treating thrombotic disorders using quercetin-containing compositions QUERCEGEN PHARMA LLC 2015-11-25 CN claimed
CN-103648530-A Protein-active agent conjugates and methods of making the same LEGOCHEM BIOSCIENCES INC 2014-03-19 CN claimed
US-20100075297-A1 PHOTOSENSITIVE POLYPEPTIDE AND METHODS OF THEIR PRODUCTION AND USE NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2010-03-25 US claimed
WO-2008085260-A2 PHOTOSENSITIVE POLYPEPTIDES AND METHODS OF THEIR PRODUCTION AND USE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2008-07-17 WO claimed
US-20070004045-A1 Analysis of large numbers of estrogens and other steroids and applications thereof THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2007-01-04 US claimed
WO-2003089921-A1 METHODS FOR SEPARATION AND DETECTION OF KETOSTEROIDS AND OTHER CARBONYL-CONTAINING COMPOUNDS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-10-30 WO claimed
WO-2026107468-A2 SYSTEMS AND METHODS FOR WRITING DATA STORED IN A POLYMER USING LIGHT IRIDIA, INC. (US) 2026-05-21 WO disclosed
US-4048323-A Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids RIKER LABORATORIES, INC. (US) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075297-A1 PHOTOSENSITIVE POLYPEPTIDE AND METHODS OF THEIR PRODUCTION AND USE NPEPPS, DNPEP, ANPEP HNF4A 4680/4885PAX8 3642/4885RAB9A 2766/4885
US-12162897-B2 1,4-sulfur-bridged polycyclic compounds containing dihydrobenzofuran structure, its preparation method and application thereof DPYD, DHPS, SULT1A1 HNF4A 1252/4885PAX8 3030/4885RAB9A 3617/4885
US-20240287099-A1 1,4-Sulfur-Bridged Polycyclic Compounds Containing Dihydrobenzofuran Structure, Its Preparation Method and Application Thereof DPYD, DHPS, SULT1A1 HNF4A 1252/4885PAX8 3030/4885RAB9A 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.