Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665945 | 0.98 | PGR (0.34) | PGRCTSKPIM1PIM3PIM2 | |
| SCHEMBL8479118 | 0.87 | OPRK1 (0.32) | CTSKDRD2 | |
| SCHEMBL8481555 | 0.86 | LMNA (0.37) | PGRDRD2 | |
| SCHEMBL8663540 | 0.85 | BRD4 (0.31) | CTSKDRD2 | |
| SCHEMBL8662767 | 0.84 | LMNA (0.37) | PGRDRD2 | |
| SCHEMBL8479790 | 0.82 | OPRK1 (0.34) | CTSKDRD2 | |
| SCHEMBL8483684 | 0.77 | NPSR1 (0.41) | DRD2 | |
| SCHEMBL8676079 | 0.76 | CCKBR (0.35) | — | |
| SCHEMBL8655139 | 0.76 | F10 (0.32) | PGR | |
| SCHEMBL8653114 | 0.75 | CCR3 (0.42) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |