Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486150 | 0.98 | PGR (0.32) | PGRCTSKPIM1PIM3PIM2 | |
| SCHEMBL8663540 | 0.87 | BRD4 (0.31) | CTSKDRD2KMT2AL3MBTL1DRD3 | |
| SCHEMBL8662767 | 0.86 | LMNA (0.37) | PGRDRD2KMT2AL3MBTL1 | |
| SCHEMBL8479118 | 0.85 | OPRK1 (0.32) | CTSKDRD2KMT2AL3MBTL1DRD3 | |
| SCHEMBL8481555 | 0.84 | LMNA (0.37) | PGRDRD2KMT2AL3MBTL1 | |
| SCHEMBL8479790 | 0.79 | OPRK1 (0.34) | CTSKDRD2KMT2AL3MBTL1DRD3 | |
| SCHEMBL8483684 | 0.78 | NPSR1 (0.41) | DRD2KMT2ADRD3 | |
| SCHEMBL8666557 | 0.76 | CCKBR (0.34) | DRD2KMT2ADRD3 | |
| SCHEMBL8653114 | 0.76 | CCR3 (0.42) | DRD2KMT2AL3MBTL1DRD3 | |
| SCHEMBL8676079 | 0.74 | CCKBR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |