Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029546 | 0.80 | OPRM1 (0.44) | TSHRHTR1ADRD2USP2HSD17B10 | |
| SCHEMBL8485006 | 0.76 | FAAH (0.43) | TSHRHTR1AHSD17B10MEN1KMT2A | |
| SCHEMBL8488103 | 0.76 | ALDH1A1 (0.41) | TSHRHTR1AHSD17B10MEN1KMT2A | |
| SCHEMBL4423181 | 0.74 | ALDH1A1 (0.49) | TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8486363 | 0.73 | AKT1 (0.58) | TSHRHTR1ADRD2USP2NPSR1 | |
| SCHEMBL7021128 | 0.72 | CNR1 (0.43) | TSHRMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7371853 | 0.66 | LTA4H (0.54) | L3MBTL1 | |
| SCHEMBL7026731 | 0.65 | POLB (0.44) | — | |
| SCHEMBL7947461 | 0.65 | HTR1A (0.50) | HTR1ADRD2HSD17B10TP53SMN1; SMN2 | |
| SCHEMBL6161203 | 0.64 | MAPK1 (0.40) | MEN1KMT2ASMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985899-A | ANTICOAGULANTS | LG CHEMICAL LTD. (KR) | 1999-11-16 | — | — | US | disclosed |
| WO-1997049673-A1 | SELECTIVE THROMBIN INHIBITORS | LG CHEMICAL LTD. (KR) | 1997-12-31 | — | — | WO | disclosed |