Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310772 | 0.86 | CES2 (0.33) | CES2CES1MAOB | |
| SCHEMBL8310471 | 0.76 | ALDH1A1 (0.36) | CES2CES1FFAR4MEN1KMT2A | |
| SCHEMBL8488170 | 0.76 | — | — | |
| SCHEMBL8310774 | 0.75 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8311178 | 0.72 | TSHR (0.42) | CES2CES1HSD17B10 | |
| SCHEMBL8312122 | 0.71 | HPD (0.36) | — | |
| SCHEMBL8309462 | 0.71 | ALB (0.36) | CES2CES1MEN1KMT2AHSD17B10 | |
| SCHEMBL8309433 | 0.70 | — | — | |
| SCHEMBL8310429 | 0.69 | LMNA (0.42) | MEN1KMT2A | |
| SCHEMBL8679249 | 0.68 | HTT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |