SCHEMBL8310772

SCHEMBL8310772

CCSC(=O)c1ccc(F)c(OCCCl)c1C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488169 0.86 CES2 (0.34) CES2CES1MAOB
SCHEMBL8312122 0.85 HPD (0.36)
SCHEMBL8310429 0.83 LMNA (0.42)
SCHEMBL8309818 0.82 LMNA (0.39) CES2CES1
SCHEMBL8310774 0.76 MEN1 (0.30)
SCHEMBL8488170 0.74
SCHEMBL8311178 0.73 TSHR (0.42) CES2CES1
SCHEMBL9303456 0.72 ADORA3 (0.35)
SCHEMBL8309433 0.69
SCHEMBL6304243 0.64 PTGER4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918056-A1 Herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1999-05-26 EP disclosed
WO-1999003856-A1 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-01-28 WO disclosed