Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493513 | 0.76 | POLB (0.33) | ADAMTS5 | |
| SCHEMBL8491013 | 0.76 | ADAMTS7 (0.34) | ADAMTS5 | |
| SCHEMBL8495085 | 0.73 | ADAMTS5 (0.34) | ADAMTS5 | |
| SCHEMBL8493598 | 0.72 | ADAMTS5 (0.38) | ADAMTS5 | |
| SCHEMBL8524338 | 0.71 | TDP1 (0.35) | ADAMTS5 | |
| SCHEMBL8497338 | 0.70 | MMP2 (0.36) | ADAMTS5 | |
| SCHEMBL8494209 | 0.70 | ADAMTS5 (0.35) | ADAMTS5 | |
| SCHEMBL15974138 | 0.69 | HSD11B1 (0.31) | — | |
| SCHEMBL8490968 | 0.68 | MMP9 (0.34) | ADAMTS5 | |
| SCHEMBL8493137 | 0.68 | ADAMTS5 (0.33) | ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |