Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25250111 | 0.79 | ALDH1A1 (0.44) | POLBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8496002 | 0.78 | DPP4 (0.45) | POLBSMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL16644665 | 0.77 | SLC6A9 (0.64) | BRD4SLC6A9 | |
| SCHEMBL21105511 | 0.76 | SLC6A9 (0.44) | POLBRAB9ANPC1BRD4HTR2A | |
| SCHEMBL7018542 | 0.74 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3451778 | 0.74 | LMNA (0.38) | POLBSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8499791 | 0.73 | SRC (0.44) | POLBRAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL8498489 | 0.72 | DPP4 (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL8499875 | 0.72 | RIPK1 (0.40) | KDM4EHTR2AHTR2CHTR2BGAA | |
| SCHEMBL28325595 | 0.72 | MAPT (0.41) | POLBSMN1; SMN2KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |