Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | PGR | P06401 | 5/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.60 |
| ▸ | AR | P10275 | 4/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503153 | 0.91 | HIF1A (0.56) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL8499317 | 0.91 | HIF1A (0.56) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL10538489 | 0.90 | NR3C1 (0.74) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL8500349 | 0.90 | NR3C1 (0.74) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL10539776 | 0.90 | NR3C1 (0.74) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL7735918 | 0.87 | ALDH1A1 (0.64) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL7741842 | 0.83 | HIF1A (0.60) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL8499567 | 0.81 | NR3C1 (0.64) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL9272798 | 0.79 | ABCB11 (0.59) | CYP3A4HIF1APGRNR3C1AR | |
| SCHEMBL9272808 | 0.79 | ABCB11 (0.59) | CYP3A4HIF1APGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939409-A | CONDENSATION OF ALDEHYDE WITH STEROIDIOL TO FORM AN ACETAL GROUPS | ASTRA AKTIEBOLAG (SE) | 1999-08-17 | — | — | US | disclosed |
| US-5888995-A | ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| US-5674861-A | GLUCOCORTICOSTEROIDS FOR LOCAL TREATMENT OF INFLAMMATORY DISORDERS | ASTRA AKTIEBOLAG (SE) | 1997-10-07 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |