Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502514 | 0.74 | IDO1 (0.40) | IDO1KMT2AMEN1PPARGALDH1A1 | |
| SCHEMBL8504764 | 0.69 | ALDH1A1 (0.38) | KMT2AMEN1THRBMAPTALDH1A1 | |
| SCHEMBL8501880 | 0.69 | ALDH1A1 (0.35) | IDO1KMT2AMEN1P2RY14COMT | |
| SCHEMBL8526361 | 0.69 | MAPT (0.43) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8504729 | 0.68 | IDO1 (0.41) | IDO1KMT2AMEN1P2RY14MAPT | |
| SCHEMBL8504693 | 0.68 | L3MBTL1 (0.38) | IDO1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8503177 | 0.68 | POLB (0.38) | IDO1KMT2AMEN1THRBMAPT | |
| SCHEMBL8504953 | 0.67 | ALDH1A1 (0.38) | IDO1KMT2AMEN1P2RY14MAPT | |
| SCHEMBL8502112 | 0.67 | IDO1 (0.40) | IDO1ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5375899 | 0.67 | LMNA (0.36) | KMT2AMEN1THRBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |