Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503177 | 0.91 | POLB (0.38) | L3MBTL1IDO1MEN1KMT2ARXFP1 | |
| SCHEMBL8502482 | 0.86 | HPGD (0.48) | L3MBTL1MEN1KMT2AMAPTPKM | |
| SCHEMBL8505812 | 0.85 | ADRB2 (0.42) | L3MBTL1IDO1MEN1KMT2ARXFP1 | |
| SCHEMBL8504781 | 0.82 | MAPK1 (0.39) | L3MBTL1IDO1MEN1KMT2ARXFP1 | |
| SCHEMBL8526361 | 0.75 | MAPT (0.43) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL8503797 | 0.75 | MAPK1 (0.44) | IDO1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL8506457 | 0.75 | IDO1 (0.39) | IDO1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8505614 | 0.73 | NLRP3 (0.41) | IDO1MAPTPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL8504696 | 0.71 | PKM (0.36) | L3MBTL1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8502188 | 0.71 | GAA (0.38) | IDO1MEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |