Acetonitrile

Acetonitrile

SCHEMBL8515909

CC#N.c1ccc(CSc2nnn[nH]2)cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
DAO P14920 1/20 0.43
ACMSD Q8TDX5 1/20 0.41
RAB9A P51151 4/20 0.41
NPC1 O15118 1/20 0.41
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
CTSB P07858 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CXCR2 P25025 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22170 0.91 DAO (0.50) ALDH1A1DAORAB9ANPC1MAOB
SCHEMBL10504274 0.76 CYP1A2 (0.45) ALDH1A1DAORAB9ANPC1L3MBTL1
Acetonitrile SCHEMBL28796785 0.75 MAPK1 (0.36) ALDH1A1MAPK1TDP1
SCHEMBL7058887 0.74 NPC1 (0.51) ALDH1A1RAB9ANPC1MAOBMAOA
SCHEMBL10503242 0.74 DAO (0.50) ALDH1A1DAORAB9ANPC1L3MBTL1
SCHEMBL31025428 0.70 MAOA (0.34) ALDH1A1DAOACMSDRAB9AMAOB
SCHEMBL11219053 0.68
SCHEMBL6408107 0.66 ALDH1A1 (0.67) ALDH1A1DAORAB9ANPC1MAOB
SCHEMBL10369265 0.66 RAB9A (0.49) ALDH1A1RAB9ANPC1
SCHEMBL9199735 0.66 LMNA (0.46) ALDH1A1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741503-A1 RNAI AGENT FOR INHIBITING AGT GENE EXPRESSION AND USE THEREOF CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) 2026-05-13 EP disclosed
US-20250346902-A1 RNAI AGENT INHIBITING PCSK9 GENE EXPRESSION AND APPLICATION THEREOF CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2025-11-13 US disclosed
CN-120019147-A Antisense oligonucleotide for inhibiting trpv1 gene expression and application thereof 石药集团中奇制药技术(石家庄)有限公司 2025-05-16 CN disclosed
CN-119816597-A DsRNA molecule for inhibiting HBV gene expression and application thereof 石药集团中奇制药技术(石家庄)有限公司 2025-04-11 CN disclosed
CN-119816596-A DsRNA molecule for inhibiting C5 gene expression and application thereof 石药集团中奇制药技术(石家庄)有限公司 2025-04-11 CN disclosed
CN-119585433-A RNAi agent for inhibiting AGT gene expression and application thereof 石药集团中奇制药技术(石家庄)有限公司 2025-03-07 CN disclosed
CN-119563025-A DsRNA molecule for inhibiting expression of LP (a) gene and application thereof 石药集团中奇制药技术(石家庄)有限公司 2025-03-04 CN disclosed
EP-4464781-A1 RNAI AGENT INHIBITING PCSK9 GENE EXPRESSION AND APPLICATION THEREOF CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) 2024-11-20 EP disclosed
CN-118786216-A RNAi agent for inhibiting PCSK9 gene expression and application thereof 石药集团中奇制药技术(石家庄)有限公司 2024-10-15 CN disclosed
CN-118679174-A Modified nucleoside monomer and double-stranded ribonucleic acid 石药集团中奇制药技术(石家庄)有限公司 2024-09-20 CN disclosed
CN-117580846-A Compounds with liver targeted delivery effect and oligonucleotide conjugates thereof 石药集团中奇制药技术(石家庄)有限公司 2024-02-20 CN disclosed
WO-2023208106-A1 COMPOUND HAVING LIVER-TARGETING DELIVERY EFFECT AND OLIGONUCLEOTIDE CONJUGATE THEREOF 石药集团中奇制药技术(石家庄)有限公司 2023-11-02 WO disclosed
US-20200172903-A1 ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF alpha-SYNUCLEIN EXPRESSION OSAKA UNIVERSITY (JP) 2020-06-04 US disclosed
EP-3628737-A1 ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF ALPHA-SYNUCLEIN EXPRESSION Osaka University (JP) 2020-04-01 EP disclosed
EP-2458005-A1 FGF21 CIS-ELEMENT BINDING SUBSTANCE Galaxy Pharma Inc. (JP) 2012-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172903-A1 ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF alpha-SYNUCLEIN EXPRESSION SNCA, ENO1, ENY2 ALDH1A1 849/4885DAO 667/4885ACMSD 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.