SCHEMBL9199735

SCHEMBL9199735

COc1cc(CSc2nnn[nH]2)cc(OC)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GALR3 O60755 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
PTGS2 P35354 1/20 0.42
BRD4 O60885 2/20 0.41
QPCT Q16769 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
POLB P06746 1/20 0.38
KDM4E B2RXH2 2/20 0.37
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5695063 0.72 BRD4 (0.47) LMNASMN1; SMN2ALDH1A1GALR3TSHR
SCHEMBL10614759 0.69 PTGS2 (0.61) ALDH1A1PTGS2HTR2AHTR2CHTR2B
SCHEMBL22170 0.69 DAO (0.50) LMNASMN1; SMN2ALDH1A1TSHRRAB9A
SCHEMBL10504274 0.68 CYP1A2 (0.45) SMN1; SMN2ALDH1A1HTTRAB9APOLB
SCHEMBL20821454 0.68 PTGS2 (0.59) LMNASMN1; SMN2ALDH1A1PTGS2HTR2A
SCHEMBL8530355 0.67 CA2 (0.48) LMNASMN1; SMN2ALDH1A1GALR3TSHR
SCHEMBL5730004 0.67 KMT2A (0.64) LMNASMN1; SMN2ALDH1A1GALR3TSHR
SCHEMBL8965661 0.67 RAB9A (0.45) LMNASMN1; SMN2ALDH1A1GALR3TSHR
SCHEMBL9842964 0.66 RAB9A (0.55) LMNASMN1; SMN2ALDH1A1RAB9APOLB
SCHEMBL6338880 0.66 TUBB4A (0.60) LMNASMN1; SMN2ALDH1A1GALR3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348139-B1 Photograhic materials and process EASTMAN KODAK CO (US) 1995-07-19 EP disclosed
EP-0348139-A2 Photograhic materials and process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-27 EP disclosed