Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SQLE | Q14534 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525820 | 0.94 | MAPT (0.38) | MAPTMAPK1PTPN1NR1H4PTGDR2 | |
| SCHEMBL7523672 | 0.92 | BACE1 (0.39) | ADORA3MAPTBACE1SQLE | |
| SCHEMBL7516405 | 0.82 | KDM4E (0.40) | MAPTMAPK1PTPN1NR1H4BACE1 | |
| SCHEMBL7524936 | 0.82 | VCAM1 (0.40) | MAPTPTGDR2TDP1MEN1KMT2A | |
| SCHEMBL7524096 | 0.81 | VCAM1 (0.38) | MAPTSMN1; SMN2KMT2ASQLE | |
| SCHEMBL8839727 | 0.80 | BACE1 (0.38) | BACE1KDM4EALDH1A1HPGD | |
| SCHEMBL7520303 | 0.80 | VCAM1 (0.33) | MAPTNR1H4POLBL3MBTL1ALDH1A1 | |
| SCHEMBL7523462 | 0.79 | VCAM1 (0.52) | SQLE | |
| SCHEMBL7526592 | 0.79 | MEN1 (0.32) | MAPTNR1H4LMNAMEN1KMT2A | |
| SCHEMBL7526551 | 0.79 | VCAM1 (0.41) | SQLEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041129-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-06 | — | — | WO | disclosed |