Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.35 |
| ▸ | SQLE | Q14534 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517276 | 0.92 | ADORA3 (0.35) | BACE1MAPTSQLEADORA3 | |
| SCHEMBL7524096 | 0.88 | VCAM1 (0.38) | MAPTTNFRSF1AVCAM1SQLEELANE | |
| SCHEMBL7520303 | 0.87 | VCAM1 (0.33) | MAPTVCAM1 | |
| SCHEMBL8839727 | 0.87 | BACE1 (0.38) | BACE1VCAM1 | |
| SCHEMBL7523462 | 0.86 | VCAM1 (0.52) | TNFRSF1AVCAM1SQLE | |
| SCHEMBL7526592 | 0.86 | MEN1 (0.32) | MAPTVCAM1SQLECYP3A4 | |
| SCHEMBL7526551 | 0.86 | VCAM1 (0.41) | TNFRSF1AVCAM1SQLE | |
| SCHEMBL7525820 | 0.85 | MAPT (0.38) | MAPTSQLEELANECYP3A4 | |
| SCHEMBL5692389 | 0.81 | CA2 (0.45) | MAPTTNFRSF1ASQLECYP3A4 | |
| SCHEMBL7516405 | 0.81 | KDM4E (0.40) | BACE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-03-10 | — | — | EP | claimed |
| WO-1997041129-A1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-06 | — | — | WO | claimed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | claimed |
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |