Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518279 | 0.92 | AKT1 (0.37) | CCKBRPDCD1CD274BRD4CREBBP | |
| SCHEMBL8518520 | 0.82 | MAPT (0.39) | ALDH1A1NPC1TP53RAB9A | |
| SCHEMBL8518880 | 0.73 | NAMPT (0.45) | CCKBRSIGMAR1ALDH1A1AKT1DRD2 | |
| SCHEMBL7400533 | 0.71 | CCKBR (0.49) | CCKBRPDCD1CD274BRD4CREBBP | |
| SCHEMBL7394047 | 0.67 | NAMPT (0.49) | CCKBRPDCD1CD274DRD2NAMPT | |
| SCHEMBL21996778 | 0.65 | POLB (0.51) | PDCD1CD274ALDH1A1TSHRBRD9 | |
| SCHEMBL31608963 | 0.64 | KMT2A (0.51) | CCKBRPDCD1CD274BRD4CREBBP | |
| SCHEMBL3838871 | 0.62 | CA12 (0.63) | ALDH1A1RAB9AAKT1NAMPT | |
| SCHEMBL5729298 | 0.62 | GLS (0.54) | BRD4CREBBPGLS | |
| SCHEMBL29072723 | 0.62 | BRD4 (0.48) | CCKBRBRD4CREBBPGLSBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |