Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520931 | 0.86 | FFAR1 (0.49) | FFAR1NR1H4ALDH1A1EPHX2MEN1 | |
| SCHEMBL8520753 | 0.84 | KMT2A (0.48) | NR1H4PLAUPLATPRSS1EPHX2 | |
| SCHEMBL8520923 | 0.80 | CA12 (0.47) | FFAR1NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL8520762 | 0.77 | KMT2A (0.44) | FFAR1NR1H4ALDH1A1EPHX2MEN1 | |
| SCHEMBL7572346 | 0.70 | ITGB3 (0.50) | PLAUALDH1A1MEN1KMT2AKCNK3 | |
| SCHEMBL7498232 | 0.69 | NR1H4 (0.41) | NR1H4PLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8520925 | 0.69 | PLAU (0.49) | NR1H4PLAUPLATF10F2R | |
| SCHEMBL7506955 | 0.68 | KMT2A (0.50) | PLAUPLATPRSS1MEN1KMT2A | |
| SCHEMBL7497380 | 0.68 | KMT2A (0.50) | PLAUPLATPRSS1MEN1KMT2A | |
| SCHEMBL8538573 | 0.68 | EPHX2 (0.41) | ALDH1A1EPHX2MEN1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-02-03 | — | — | EP | claimed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |