SCHEMBL852777

SCHEMBL852777

[CH]=Cc1ccc(OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
CYP2A6 P11509 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
KDM4E B2RXH2 4/20 0.56
CYP3A4 P08684 2/20 0.56
LMNA P02545 2/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
TRPA1 O75762 1/20 0.54
RELA Q04206 1/20 0.54
CYP1A2 P05177 3/20 0.52
CYP1A1 P04798 3/20 0.52
CYP1B1 Q16678 3/20 0.52
ESR1 P03372 2/20 0.52
PTGS2 P35354 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480958 0.93 ALDH1A1 (0.52) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL5274848 0.80 ALDH1A1 (0.38) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL13790336 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
SCHEMBL14950253 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
SCHEMBL27883 0.78 CA12 (0.65) ALDH1A1CYP2A6CA12CA1CA2
SCHEMBL631998 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
SCHEMBL699458 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
SCHEMBL4881152 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
SCHEMBL699457 0.78 RELA (0.81) ALDH1A1KDM4ECYP3A4LMNATP53
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) ALDH1A1CYP2A6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444324-A Application of organic lead salt, composition and preparation method thereof 中国科学院上海有机化学研究所 2023-07-18 CN claimed
CN-114957312-A Aryl silicon compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-30 CN claimed
CN-113105459-A Triazolopyrimidine derivative and preparation method and application thereof 五邑大学 2021-07-13 CN claimed
CN-106947469-B Isoindole boron-doped fluorescent dye and preparation method and application thereof 安徽师范大学 2020-04-17 CN claimed
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-09-04 US claimed
US-9949970-B2 Synthesis of new benzothiazole derivatives as potential anti-tubercular agents COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-04-24 US claimed
EP-3051946-B1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2017-11-29 EP claimed
CN-107353854-A A kind of OCA optical cements and OCA optical adhesive films 东莞市纳利光学材料有限公司 2017-11-17 CN claimed
US-20160237035-A1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 US claimed
EP-3051946-A1 USE OF SUBSTITUTED DIHYDRO-OXINDOLYL SULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS Bayer CropScience Aktiengesellschaft (DE) 2016-08-10 EP claimed
EP-0793674-A1 HUMAN NEUTROPHIL ELASTASE INHIBITORS CORTECH, INC. (US) 1997-09-10 EP claimed
US-5618792-A USEFUL FOR TREATING ACUTE RESPIRATORY DISEASES, AND MYOCARDIAL ISHCEMIA-REPERFUSION INJURY CORTECH, INC. (US) 1997-04-08 US claimed
WO-1996016080-A1 HUMAN NEUTROPHIL ELASTASE INHIBITORS CORTECH, INC. (US) 1996-05-30 WO claimed
US-5338640-A Alkali-developable; resistance to oxygen etching; multilayer photoresists; photolithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US claimed
US-5278273-A Additional polymer FUJI PHOTO FILM CO., LTD. (JP) 1994-01-11 US claimed
US-5276124-A Ladder polymers, photoresists, lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1994-01-04 US claimed
US-5252686-A Siloxane polymers and positive working light-sensitive compositions comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US claimed
US-5216105-A SILICONE POLYMERS AND POSITIVE WORKING LIGHT-SENSITIVE COMPOSITIONS COMPRISING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1993-06-01 US claimed
US-4448787-A ANTIALLERGENS LILLY INDUSTRIES LIMITED (GB) 1984-05-15 US claimed
US-RE28698-E Electrophotographic material containing sensitizers MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants SQOR, DHPS, QDPR ALDH1A1 652/4885CYP2A6 537/4885CA12 4304/4885
US-20160237035-A1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS SQOR, DHPS, QDPR ALDH1A1 652/4885CYP2A6 537/4885CA12 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.