Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533511 | 0.89 | SLC6A9 (0.50) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8529827 | 0.87 | ALDH1A1 (0.42) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8530758 | 0.82 | SLC6A9 (0.45) | SLC6A9ALDH1A1EPHX1 | |
| SCHEMBL8531521 | 0.81 | SLC6A9 (0.42) | SLC6A9ALDH1A1CA2CA4EPHX1 | |
| SCHEMBL8533467 | 0.80 | AGBL2 (0.55) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8530695 | 0.75 | HPGD (0.48) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8533329 | 0.73 | SLC6A9 (0.48) | SLC6A9ALDH1A1EPHX1 | |
| SCHEMBL8536289 | 0.72 | MEN1 (0.53) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL8533938 | 0.72 | ALDH1A1 (0.53) | SLC6A9ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL10597129 | 0.72 | ALDH1A1 (0.47) | SLC6A9ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |