Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533151 | 0.92 | KEAP1 (0.47) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL7262682 | 0.75 | KEAP1 (0.43) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL3776295 | 0.74 | KEAP1 (0.54) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL27228693 | 0.69 | MMP2 (0.44) | KEAP1NFE2L2MMP2MMP13L3MBTL1 | |
| SCHEMBL4297055 | 0.69 | MMP2 (0.44) | KEAP1NFE2L2MMP2MMP13L3MBTL1 | |
| SCHEMBL12355594 | 0.67 | ALDH1A1 (0.56) | KEAP1NFE2L2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6307961 | 0.67 | KEAP1 (0.51) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL12596097 | 0.67 | TRIM24 (0.51) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL12355592 | 0.67 | MEP1B (0.46) | KEAP1NFE2L2TRIM24BRD1BRPF1 | |
| SCHEMBL29156174 | 0.66 | PKM (0.54) | KEAP1NFE2L2MMP2MMP13L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831001-A | ADMINISTERING OLIGOPEPTIDE WITH ARGININE UNITS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-11-03 | — | — | US | disclosed |