SCHEMBL8535552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28005739	0.77	KDM4E (0.53)	HTR1AHTR2CKDM4EALDH1A1SMN1; SMN2
	SCHEMBL8426568	0.75	MAPT (0.50)	KDM4EALDH1A1SMN1; SMN2CYP2A6CYP19A1
	SCHEMBL8536271	0.74	NOTUM (0.50)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL7099717	0.73	HTR1A (0.45)	HTR1AHTR2CKDM4EALDH1A1SMN1; SMN2
	SCHEMBL8404071	0.73	GABRP (0.48)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL19961724	0.73	CYP19A1 (0.50)	KDM4EALDH1A1SMN1; SMN2CYP2A6CYP1A2
	SCHEMBL27905069	0.72	SMN1; SMN2 (0.72)	HTR1AHTR2CKDM4EALDH1A1SMN1; SMN2
	SCHEMBL9091484	0.71	CYP19A1 (0.57)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL28055039	0.71	HTR1A (0.50)	HTR1AHTR2CCYP19A1CYP17A1CYP11B1
	SCHEMBL11926858	0.69	CYP2A6 (0.62)	HTR1AHTR2CKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.