Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537910 | 0.88 | NCF1 (0.34) | NCF1NPC1CDK1CDK2RAB9A | |
| SCHEMBL8539150 | 0.81 | ADRA2A (0.39) | KMT2AMEN1LMNAL3MBTL1KDM4E | |
| SCHEMBL8538654 | 0.76 | PRMT5 (0.37) | KMT2AMEN1LMNAKDM4E | |
| SCHEMBL8536634 | 0.73 | PARP1 (0.36) | CDK1CDK2KMT2AMEN1 | |
| SCHEMBL8537561 | 0.69 | LMNA (0.33) | LMNA | |
| SCHEMBL9241626 | 0.69 | — | — | |
| SCHEMBL9241622 | 0.69 | ACKR3 (0.32) | — | |
| SCHEMBL30581190 | 0.66 | CA2 (0.42) | LMNAHTTKDM4E | |
| SCHEMBL8535592 | 0.66 | PTGS1 (0.40) | KDM4E | |
| SCHEMBL8415243 | 0.66 | CA2 (0.42) | LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048246-C | Indazolesulfonylurea derivative, use thereof, and intermediate for production thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2000-01-12 | — | — | CN | disclosed |