Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541231 | 0.84 | PARP1 (0.40) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL8542589 | 0.74 | KMT2A (0.43) | ALDH1A1RAB9ANPC1ITGB3ITGA2B | |
| SCHEMBL7861970 | 0.70 | ITGB3 (0.76) | ALDH1A1ITGB3ITGA2BSIRT1KMT2A | |
| SCHEMBL7373419 | 0.69 | ITGB3 (0.66) | ALDH1A1NPC1ITGB3ITGA2BMEN1 | |
| SCHEMBL7375114 | 0.69 | ITGB3 (0.51) | ALDH1A1HPGDITGB3ITGA2B | |
| SCHEMBL8544650 | 0.69 | PARP1 (0.42) | ALDH1A1RAB9ASIRT1MEN1KMT2A | |
| SCHEMBL7496410 | 0.68 | PKM (0.53) | ALDH1A1MAPTITGB3ITGA2BSIRT1 | |
| SCHEMBL7496407 | 0.68 | PKM (0.53) | ALDH1A1MAPTITGB3ITGA2BSIRT1 | |
| SCHEMBL5354517 | 0.68 | L3MBTL1 (0.60) | ALDH1A1MAPTGAARAB9AHTT | |
| SCHEMBL7450519 | 0.68 | PPARG (0.65) | ALDH1A1HPGDRAB9ANPC1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |