Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542592 | 0.88 | P2RX1 (0.37) | P2RX1PTGS1RXFP1CFTRKDM4E | |
| SCHEMBL8538615 | 0.69 | RXFP1 (0.40) | RXFP1MAOBKDM4E | |
| SCHEMBL8538589 | 0.64 | P2RX1 (0.41) | P2RX1MAOBMAPTHTT | |
| SCHEMBL8538587 | 0.64 | P2RX1 (0.39) | P2RX1MAOBMAPT | |
| SCHEMBL8538088 | 0.64 | P2RX1 (0.38) | P2RX1RXFP1MAPTHTT | |
| SCHEMBL8535813 | 0.63 | TAS2R14 (0.36) | P2RX1PTGS1RXFP1POLB | |
| SCHEMBL8538575 | 0.61 | RAB9A (0.40) | MAPTKDM4EPOLBHTT | |
| SCHEMBL8541184 | 0.61 | RAB9A (0.39) | MAPTKDM4EPOLBHTT | |
| SCHEMBL7572355 | 0.61 | ALDH1A1 (0.44) | MAPTKDM4E | |
| SCHEMBL177123 | 0.61 | ALDH1A1 (0.67) | CFTRMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |