Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241898 | 0.88 | ALOX15 (0.31) | — | |
| SCHEMBL29184106 | 0.86 | ALDH1A1 (0.33) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL28399900 | 0.84 | FDPS (0.30) | FDPS | |
| SCHEMBL13308357 | 0.78 | — | — | |
| SCHEMBL25288074 | 0.74 | LMNA (0.38) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL20298943 | 0.74 | — | — | |
| SCHEMBL13934054 | 0.74 | FDPS (0.30) | FDPS | |
| SCHEMBL5445954 | 0.74 | CA2 (0.33) | EPHX1CA1CA2 | |
| SCHEMBL9009536 | 0.73 | — | — | |
| SCHEMBL11589986 | 0.72 | CES2 (0.37) | HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999059989-A1 | PROCESS FOR THE PREPARATION OF A BENZO FUSED HETEROCYCLO SULFONYL HALIDE INTERMEDIATE | G.D. SEARLE & CO. (US) | 1999-11-25 | — | — | WO | disclosed |