Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 8/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546367 | 0.87 | PPARD (0.46) | ALDH1A1PPARDPPARAPPARGSMN1; SMN2 | |
| SCHEMBL8547901 | 0.84 | POLB (0.43) | GAAL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL8548183 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1TRPM8KDM4ESYK | |
| SCHEMBL8549346 | 0.81 | LMNA (0.53) | ALDH1A1L3MBTL1MAPTTRPM8POLB | |
| SCHEMBL8548861 | 0.79 | POLB (0.39) | ALDH1A1GAAL3MBTL1MEN1MAPT | |
| SCHEMBL8549230 | 0.79 | TRPM8 (0.42) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL8551330 | 0.78 | TRPM8 (0.39) | ALDH1A1MEN1MAPTKMT2APPARD | |
| SCHEMBL8666788 | 0.78 | TRPM8 (0.41) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL8546592 | 0.74 | ALDH1A1 (0.40) | ALDH1A1GAAL3MBTL1MEN1MAPT | |
| SCHEMBL8545588 | 0.74 | TRPM8 (0.41) | ALDH1A1GAAL3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |