SCHEMBL8547624

SCHEMBL8547624

CCON(O)c1nc2nc(C)[nH]c2c(=O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.31
PNP P00491 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048224 0.76 NUDT1 (0.42) MAT2APNP
SCHEMBL26155922 0.72 PNP (0.48) PNP
SCHEMBL27666714 0.71 MAT2A (0.31) MAT2APNP
SCHEMBL27456995 0.69
SCHEMBL9275474 0.68 XDH (0.38) PNP
SCHEMBL9275484 0.65 PNP (0.48) PNP
SCHEMBL22883 0.64 PNP (0.73) PNP
SCHEMBL16513131 0.64 PNP (0.41) PNP
SCHEMBL7536657 0.64 HCAR2 (0.33) PNP
SCHEMBL7536668 0.63 PDE5A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891374-A4 UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF UNIV COLUMBIA (US) 1999-04-07 EP disclosed
EP-0891374-A1 UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF The Trustees of Columbia University in the City of New York (US) 1999-01-20 EP disclosed
WO-1997027208-A1 UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-07-31 WO disclosed