Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543461 | 0.83 | KDM4E (0.42) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8545150 | 0.80 | GAA (0.43) | KDM4ECYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL8550467 | 0.76 | CYP1A2 (0.50) | KDM4ECYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL8543469 | 0.76 | KDM4E (0.41) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8546692 | 0.73 | CYP1A2 (0.50) | KDM4ECYP1A2CYP3A4CYP2C9MEN1 | |
| SCHEMBL3288484 | 0.72 | CYP1A2 (0.49) | KDM4ECYP1A2CYP3A4CYP2C9MEN1 | |
| SCHEMBL8551235 | 0.72 | ALDH1A1 (0.39) | KDM4ECYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL8551379 | 0.70 | KDM4E (0.49) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8550254 | 0.70 | TRPM8 (0.46) | CYP1A2CYP2C9ALDH1A1LMNAGAA | |
| SCHEMBL8549346 | 0.70 | LMNA (0.53) | KDM4ECYP1A2CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |