Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548048 | 0.83 | ITGB3 (0.56) | KDM4EHPGDALDH1A1HSD17B10CHRM4 | |
| SCHEMBL12639924 | 0.81 | GPR119 (0.56) | GPBAR1GPR119KDM4EPOLBRXFP1 | |
| SCHEMBL22770920 | 0.80 | ALDH1A1 (0.48) | KDM4EPOLBHPGDALDH1A1RXFP1 | |
| SCHEMBL22771168 | 0.79 | L3MBTL1 (0.61) | KDM4EPOLBHPGDALDH1A1CHRM4 | |
| SCHEMBL19658641 | 0.77 | CKS1B (0.53) | GPR119RXFP1RIPK1LSSCHRM4 | |
| SCHEMBL3861796 | 0.77 | KDM4E (0.65) | GPBAR1GPR119KDM4EALDH1A1RXFP1 | |
| SCHEMBL6181710 | 0.76 | RIPK1 (0.58) | GPBAR1GPR119KDM4EHPGDRIPK1 | |
| Hydrochloric Acid SCHEMBL1990072 | 0.75 | RIPK1 (0.57) | GPBAR1GPR119KDM4EHPGDRIPK1 | |
| SCHEMBL6180885 | 0.74 | MAPT (0.53) | GPR119KDM4EPOLBALDH1A1RIPK1 | |
| SCHEMBL6792902 | 0.74 | PKM (0.52) | GPBAR1KDM4EPOLBRIPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |