Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550905 | 0.89 | HSD17B10 (0.45) | HSD17B10PTPN1GPR35HPGDMAPT | |
| SCHEMBL8549323 | 0.86 | HSD17B10 (0.54) | HSD17B10PTPN1GPR35HPGDMAPT | |
| SCHEMBL8548248 | 0.82 | THRA (0.49) | HPGDMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL8546447 | 0.79 | HPGD (0.46) | HSD17B10HPGDMAPTALDH1A1LMNA | |
| SCHEMBL4113651 | 0.76 | CA2 (0.48) | HSD17B10PTPN1HPGDMAPTCA2 | |
| SCHEMBL8549612 | 0.73 | HSD17B10 (0.59) | HSD17B10PTPN1GPR35HPGDMAPT | |
| SCHEMBL3709174 | 0.73 | HSD17B10 (0.49) | HSD17B10HPGDMAPTCA2CA4 | |
| SCHEMBL9258995 | 0.72 | CA2 (0.48) | HSD17B10PTPN1GPR35HPGDMAPT | |
| SCHEMBL7128064 | 0.71 | GPR35 (0.40) | HSD17B10PTPN1GPR35HPGDMAPT | |
| SCHEMBL8551491 | 0.71 | THRA (0.49) | HPGDMAPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |