Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489097 | 0.84 | HTR1D (0.49) | DRD2CCR2 | |
| SCHEMBL8552510 | 0.84 | DRD2 (0.40) | P2RY1KCNH2DRD2SLC6A4 | |
| SCHEMBL8552507 | 0.82 | DRD2 (0.39) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8551516 | 0.80 | DRD2 (0.40) | P2RY1KCNH2DRD2SLC6A4 | |
| SCHEMBL8547062 | 0.78 | DRD2 (0.46) | KCNH2DRD2SLC6A4CCR2 | |
| SCHEMBL8704937 | 0.76 | DRD2 (0.44) | ALDH1A1P2RY1KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL8552657 | 0.76 | L3MBTL1 (0.49) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL8552124 | 0.76 | DRD2 (0.43) | ALDH1A1P2RY1KCNH2MAPTKMT2A | |
| SCHEMBL8550058 | 0.76 | DRD2 (0.41) | DRD2SLC6A4TSHR | |
| SCHEMBL8703019 | 0.76 | DRD2 (0.53) | NPC1RAB9ADRD2SLC6A4CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |