Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551669 | 0.88 | HTT (0.68) | FPR1LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL8554553 | 0.84 | PTGS2 (0.66) | FPR1LMNAGAAL3MBTL1 | |
| SCHEMBL8553556 | 0.78 | CYP2C9 (0.70) | LMNAKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL8556342 | 0.78 | PTGS2 (0.72) | FPR1LMNAKMT2AALDH1A1 | |
| SCHEMBL8550650 | 0.75 | FPR1 (0.53) | FPR1LMNAKMT2AGAAALDH1A1 | |
| SCHEMBL8551416 | 0.75 | ALDH1A1 (0.70) | LMNAGAAALDH1A1POLBNPSR1 | |
| SCHEMBL8551424 | 0.75 | PTGS1 (0.65) | FPR1GAANPSR1 | |
| SCHEMBL6436108 | 0.74 | L3MBTL1 (0.69) | LMNAKMT2AGAAALDH1A1POLB | |
| SCHEMBL8553129 | 0.74 | PTGS2 (0.66) | FPR1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL8550834 | 0.74 | PTGS2 (0.66) | FPR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |