Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | LSS | P48449 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 3/20 | 0.38 |
| ▸ | ATP4B | P51164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551954 | 0.83 | LMNA (0.50) | LMNACYP1A2CYP2D6LSSCA1 | |
| SCHEMBL8552900 | 0.82 | LMNA (0.53) | LMNACYP1A2CYP2D6LSSMAPT | |
| SCHEMBL8361490 | 0.82 | LMNA (0.53) | LMNACYP1A2CYP2D6LSSMAPT | |
| SCHEMBL8357948 | 0.81 | NPC1 (0.42) | LMNACYP1A2CYP2D6MAPTKMT2A | |
| SCHEMBL8548836 | 0.81 | LMNA (0.56) | LMNACYP1A2CYP2D6LSSMAPT | |
| SCHEMBL8550339 | 0.80 | LMNA (0.55) | LMNACYP1A2CYP2D6LSSKMT2A | |
| SCHEMBL8355802 | 0.80 | HTR1B (0.39) | LMNAMAPTKMT2ANPC1PKM | |
| SCHEMBL8358060 | 0.79 | LMNA (0.63) | LMNACYP1A2CYP2D6MAPTCA1 | |
| SCHEMBL8551252 | 0.79 | LMNA (0.50) | LMNACYP1A2CYP2D6LSSMAPT | |
| SCHEMBL8357496 | 0.78 | DRD2 (0.53) | CYP1A2CYP2D6MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |