Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551274 | 0.89 | PLAAT3 (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL8550399 | 0.88 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL8551925 | 0.88 | GRIK1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2CYP2C9 | |
| SCHEMBL8548352 | 0.87 | SMN1; SMN2 (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL8555352 | 0.86 | NLRP3 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2AKR1C3 | |
| SCHEMBL8550868 | 0.86 | AKR1C3 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL8550978 | 0.85 | MAPT (0.46) | ALDH1A1SMN1; SMN2AKR1C3LMNAPLAAT3 | |
| SCHEMBL8547353 | 0.84 | PLAAT3 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2AKR1C3 | |
| SCHEMBL8593809 | 0.84 | FBP1 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8547323 | 0.83 | MAPT (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |