Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 4/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552120 | 0.77 | RAB9A (0.35) | GAANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8547344 | 0.77 | TGM2 (0.38) | GAATGM2ZDHHC20ZDHHC2MEN1 | |
| SCHEMBL8547481 | 0.75 | TGM2 (0.43) | TGM2ZDHHC20ZDHHC2NPC1RAB9A | |
| SCHEMBL8555523 | 0.74 | TGM2 (0.42) | GAATGM2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1508505 | 0.73 | MEN1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL1508506 | 0.73 | MEN1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8551267 | 0.73 | ZDHHC20 (0.42) | GAATGM2ZDHHC20ZDHHC2LMNA | |
| SCHEMBL8144690 | 0.73 | HTT (0.40) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL8555564 | 0.73 | NFE2L2 (0.45) | GAATGM2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8549538 | 0.73 | GRIK1 (0.46) | TGM2ZDHHC20ZDHHC2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |