Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653253 | 0.80 | TP53 (0.41) | HTTTP53LMNATSHRALDH1A1 | |
| SCHEMBL8554310 | 0.71 | TSHR (0.48) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8553942 | 0.70 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8602443 | 0.70 | HTT (0.51) | HTTTSHRALDH1A1 | |
| SCHEMBL8632952 | 0.69 | SIRT1 (0.41) | TP53LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8555413 | 0.68 | HTT (0.52) | HTTTSHRALDH1A1SMN1; SMN2SIRT1 | |
| SCHEMBL8628591 | 0.68 | LOXL2 (0.41) | TP53LMNATSHRALDH1A1MAPK1 | |
| SCHEMBL8631498 | 0.67 | TSHR (0.43) | HTTTP53LMNATSHRALDH1A1 | |
| SCHEMBL3253076 | 0.66 | ALOX15 (0.70) | HTTTP53LMNATSHRALDH1A1 | |
| SCHEMBL8596034 | 0.64 | TSHR (0.48) | HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |