Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549475 | 0.78 | SMN1; SMN2 (0.65) | HTT | |
| SCHEMBL8552418 | 0.73 | MGLL (0.35) | BCHEACHEHTT | |
| SCHEMBL5031358 | 0.72 | HRH3 (0.53) | BCHELMNAHRH3 | |
| SCHEMBL5029372 | 0.72 | HRH3 (0.56) | BCHELMNAHRH3 | |
| SCHEMBL8549480 | 0.71 | BCHE (0.35) | BCHEACHELMNA | |
| SCHEMBL30128338 | 0.70 | LTA4H (0.56) | LMNAHTTHRH3 | |
| SCHEMBL4663018 | 0.70 | LTA4H (0.60) | LMNAHTTHRH3 | |
| SCHEMBL2080921 | 0.70 | TSHR (0.48) | HRH3 | |
| SCHEMBL7301909 | 0.69 | LMNA (0.59) | LMNAHRH3 | |
| SCHEMBL26096555 | 0.69 | ACHE (0.72) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |